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MGMT

Catalog Number: EXA-X2730P

 

Details

The MGMT enzyme is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Additional Information

Suppliers Exalpha
Presentation N/A