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Fluorogenic SIRT substrate 1

Catalog Number: BPS-50080

 

Details

A fluorogenic, acetylated peptide substrate for SIRTs. It is a suitable substrate for SIRT1, SIRT2 and SIRT3 (tested so far). The substrate is based on residues 379-382 (Arg-His-Lys-Lys) of p53, a site of regulatory acetylation by the p300 and CBP acetyltransferases on lysines 381 and 382. This substrate fluoresces at excitation 350-380 nm, emission at 440-460 nm. The substrate should be used in conjunction with SIRT Developer.

Additional Information

Suppliers BPS Bioscience
Presentation 500 nmole