It is with great pride and immense pleasure that we introduce the Creative Bioarray QualiStem® Alkaline Phosphatase Live Staining Kit which provides a fast, simple and sensitive method for AP detection without fixing the cells. The reagent is nontoxic to the cells and the fluorescent signal will be discharged from the cells by exocytosis completely within two hours after removal of the staining solution, allowing the cell to be used for follow-up studies
Details
Sphingomyelin Synthase is a bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) in addition to performing the inverse reaction. The direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. It directly and specifically recognizes the choline head group on the substrate. It also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. It may not function strictly as a SM synthase and is inhibited by bacterial PC-phospholipase C inhibitor D609. It is localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. It can be possibly present on the brain, heart, kidney, liver, muscle and stomach.
Additional Information
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