It is with great pride and immense pleasure that we introduce the Creative Bioarray QualiStem® Alkaline Phosphatase Live Staining Kit which provides a fast, simple and sensitive method for AP detection without fixing the cells. The reagent is nontoxic to the cells and the fluorescent signal will be discharged from the cells by exocytosis completely within two hours after removal of the staining solution, allowing the cell to be used for follow-up studies
Details
Recognizes a single band of 39-42kDa, identified as the G?i1 protein. This antibody is highly specific to G?i1 and shows no cross-reaction with transducin, G?o, G?i2, G?i3, or G?s. ADP-ribosylation of ?i1 protein does not alter the reactivity of R4.5 MAb. GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation.
Additional Information
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