It is with great pride and immense pleasure that we introduce the Creative Bioarray QualiStem® Alkaline Phosphatase Live Staining Kit which provides a fast, simple and sensitive method for AP detection without fixing the cells. The reagent is nontoxic to the cells and the fluorescent signal will be discharged from the cells by exocytosis completely within two hours after removal of the staining solution, allowing the cell to be used for follow-up studies
Details
Recognizes a protein of 59kDa, which is identified as Fyn. p59fyn is a membrane-associated non-receptor protein tyrosine kinase that belongs to the Src-family of kinases. This antibody shows no cross-reaction with other members of the Src protein kinase family. Its epitope spans between aa 26-75 of the unique region of p59fyn. The unique N-terminal domain of p59fyn interacts with the CD3 and z chains of the TcR. p59fyn can bind other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of fyn activity. p59fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.
Additional Information
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