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Actin (alpha Smooth Muscle)

Catalog Number: EXA-X1722M

 

Details

Among the six actin isoforms described in mammals, two are found in virtually all cells (?? and ??cytoplasmic), two are detected in smooth muscle cells (?? and ?-smooth muscle) and two are present in striated muscles, one predominantly in skeletal (?-skeletal) and one in cardiac (?-cardiac) muscle cells. These actin isoforms differ slightly in their N-terminus and the sequences of each of them are perfectly conserved in higher vertebrates. Alpha-smooth muscle actin is abundant in vascular and visceral smooth muscle cells. In addition, it has also been shown to appear in stress fibers of fibroblastic cells during pathological situations involving contractile phenomena such as wound healing and fibrocontractive diseases.

Additional Information

Suppliers Exalpha
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