It is with great pride and immense pleasure that we introduce the Creative Bioarray QualiStem® Alkaline Phosphatase Live Staining Kit which provides a fast, simple and sensitive method for AP detection without fixing the cells. The reagent is nontoxic to the cells and the fluorescent signal will be discharged from the cells by exocytosis completely within two hours after removal of the staining solution, allowing the cell to be used for follow-up studies
Details
Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin1. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFR? and Ret receptor tyrosine kinase GFR?2. Following the findings of GFR?-1 and -2, a novel receptor in GFR? family was identified very recently from human and mouse and designated GFR?-33-7. GFR?-3 binds persephin, thus, persephin, GFR?-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.
Additional Information
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