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Extracellular Signal-Regulated Kinase 1 (MAPK3/ERK1)

Catalog Number: EXA-X2259P

 

Details

Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Activated by tyrosine phosphorylation in response to insulin and NGF. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 By similarity. Phosphorylates heat shock factor protein 4 (HSF4).

Additional Information

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