Olaf Pharmaceuticals develops high quality extracellular matrix products for various purposes including cell attachment, cell growth, cell differentiation, cell migration, Stem cell research, tissue engineering and tissue morphogenesis. Olaf Pharmaceuticals is currently offering a range of Type I collagen products derived from various sources.  We also develop tissue-engineered products for a number of research, drug delivery -related applications, such as vasculature.

Product Applications:

All of our products are manufactured in a clean room environment, and have been tested by outside labs in the United States and United Kingdom.  Our CollaGel Hydrogels can be used as two- or three-dimensional scaffolds for cells; it mimics the natural environment of cells, both chemically and physically.

All you have to do is:

Step 1: Thaw your CollaGel Hydrogel Soft solutionStep           Step 2: Add your cell suspensions              Step 3: Gel in 15 minutes at room temp

Our CollaGel Hydrogel can help in:

Adult Stem Cell development                 Embryonic Stem cell development                        Fibrosis                   

Cosmetic toxicology                               Hepatocyte functionNeuronal branching                Wound healing assays

Cell invasion assay                                 Migration assays                                                Stem cell self-renewal

Lineage specification                              Cancer cell phenotype                                         Bioprinting

Our CollaGel Hydrogel matches the softness of the body's tissues. It can be used to culture neurons in an environment as soft as the brain, cardiomyocytes on the stiffness of muscle, or whatever your cells' tissue of origin may be. In a 3D tissue model, our CollaGel Hydrogel helps the cells build stronger basement membranes. Our CollaGel Hydrogel has been used to form small tube-like structures in combination with Human Umbilical Vein Endothelial Cells (HUVEC) in a 3D model. Our CollaGel Hydrogel can also be used for 3D printing without worrying about the needles in your machine been broken due to the fast gelling process.

 One neat thing we have also been able to do with cells embedded within the gels have been the ability to interrogate themusing assays which we have seen to penetrate the gels for us to test the cells this is important for engineering functionaltissues and for using these gels for making model cultures (from disease to healthy ones)