Our kidneys have an important function: to remove wastes and water from the blood to form urine. Kidney failure can result from many factors including high blood pressure, diabetic kidney disease, and the overuse of medications.


In this newsletter we discuss a variety of research assays to easily and reliably study renal function.


Creatinine Assay

Altered creatinine levels can indicate kidney dysfunction or other medical conditions that result in lower renal blood flow. 

Our Urinary Creatinine Assay Kit easily measures creatinine levels in urine samples as low as 300 µg/dL with a standard plate reader. 


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Kidney Injury Molecule-1 (KIM-1) Assays

KIM-1 is a useful biomarker for early preclinical screens for kidney disease, and it has been shown to outperform traditional biomarkers of kidney injury. Our kits can detect KIM-1 in human or rat urine by lateral flow assay or ELISA.  Our lateral flow format is a rapid 15 minute strip test for semi-quantitative detection, and the ELISA format provides quantitative results as low as 300 pg/mL.


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Protein Carbamylation ELISA

Our Protein Carbamylation ELISA Kit is an enzyme immunoassay developed for rapid detection and quantitation of protein carbamylation. It is compatible with cell lysates, blood samples, and purified proteins and detects protein carbamylation as low as 4 ng/mL.


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Urea Assay

Urea is the primary vehicle for removing toxic ammonia from the body and can be an indicator of pre-renal, renal, and post renal uremia. High levels of urea can lead to many health problems such as liver or renal dysfunction, cardiac decomposition, tubular necrosis, and infection. Our Urea Assay Kit reliably measures urea levels in urine, serum, plasma, cell lysates, or tissue homogenates.


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Uric Acid Assay

Uric acid is a metabolic breakdown of purine neclueotides, and high levels can indicate problems such as kidney stones or kidney failure. Our Uric Acid/Uricase Assay Kit is a sensitive, quantitative fluorometric assay for measuring uric acid or uricase concentrations. 


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