Activating B cells with Anti-IgD eliminates problematic interference from high levels of circulating serum IgM experienced with Anti-IgM B cell activation. |
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eBioscience's new monoclonal Anti-Mouse IgD functional grade purified antibody (clone 10.4.22) reacts with the a allotype of mouse IgD which is expressed by mature peripheral B cells and thereby activates B cells. This new clone allows for highly controlled, reproducible monoclonal activation of mouse B cells. Clone 10.4.22 also recognizes a different epitope from our anti mouse IgD (clone 11-26c). Our Anti-Mouse IgD polyclonal goat antiserum reacts with the delta heavy chain of mouse IgD and is a useful polyclonal activator of B cells (in vitro or in vivo).
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