Monitoring DNA methylation at the single-cell level

 

In this week’s Cell publication, researchers from MIT and Whitehead Institute for Biomedical Research document the introduction of a green fluorescence protein-based reporter method to study DNA methylation patterns in individual cells.  This technique captures the endogenous methylation state of promoters and non-coding regions, and can trace methylation changes both in vitro and in vivo.

dnamethylation

Keeping track on your reporters

Browse our range of state-of-the-art reporter products to assist you with looking for changes in expression. 

Choose from:  BiotinGreen fluorescence proteinRed fluorescent proteinLuciferase and  Beta-galactosidase,